讲座题目： Biobehavioural markers of individual vulnerability to addiction: role of the environment
主 持 人： 赵晶晶 研究员
讲 座 人： David Belin博士
地 点： 雁塔校区教学九楼9209学术报告厅
Dr David Belin is a Lecturer in Behavioural Neuroscience at the Department of Psychology of the University of Cambridge. He developed the first preclinical model of cocaine addiction based in the multiple clinical criteria as defined in humans. He also investigated the corticostriatal mechanisms of cocaine seeking habits and the relationships between impulsivity and compulsive cocaine self-administration, leading to a breakthrough in our understanding of the neurological and psychological mechanisms subserving individual vulnerability to cocaine addiction. Dr David Belin has authored over 50 publications and received the Mémain-Pelletier Award from the French Academy of Science and the Young Investigator Award from the European Behavioural Pharmacology Society.
Drug addiction results from the interaction between a vulnerable individual, a drug and an environment which interactions and their contribution to the transition from volitional to compulsive drug seeking habits, the hallmark of addiction, are yet to be understood. However, over the last decade the development of novel preclinical models of addiction in rodents, factoring in the notion of inter-individual differences with the operationalisation of the main clinical features of addiction in humans have helped shed a new light on the mechanisms subserving this inter-individual vulnerability to develop compulsive drug seeking habits. The presentations will delve into the psychological constructs of the most recent preclinical models of addiction and will investigate the recent breakthrough in the psychological and neural substrates of the propensity to use drugs and to switch from controlled drug use to maladaptive drug seeking habits.